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Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4(+) T Cells
Kaposi's sarcoma-associated herpesvirus (KSHV) has tropism for B lymphocytes, in which it establishes latency, and can also cause lymphoproliferative disorders of these cells manifesting as primary effusion lymphoma (PEL) and multicentric Castleman disease (MCD). T cell immunity is vital for th...
Autores principales: | Nicol, Samantha M., Sabbah, Shereen, Brulois, Kevin F., Jung, Jae U., Bell, Andrew I., Hislop, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810529/ https://www.ncbi.nlm.nih.gov/pubmed/26819313 http://dx.doi.org/10.1128/JVI.02377-15 |
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