Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?

BACKGROUND: Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice have great importance in evaluating the function of genes. However, their utility depends on the maintenance of this true congenic nature. Although, accumulating evidence suggests tha...

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Detalles Bibliográficos
Autores principales: McClelland, Erin E, Damjanovich, Kristy, Gardner, Kyle, Groesbeck, Zack J, Ma, Maggie S, Nibley, Megan, Richardson, Kelly S, Wilkinson, Maureen, Morrison, Linda C, Bernhardt, Paul, Potts, Wayne K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC481063/
https://www.ncbi.nlm.nih.gov/pubmed/15245582
http://dx.doi.org/10.1186/1471-2172-5-14

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