Polyprotein-Driven Formation of Two Interdependent Sets of Complexes Supporting Hepatitis C Virus Genome Replication

Hepatitis C virus (HCV) requires proteins from the NS3-NS5B polyprotein to create a replicase unit for replication of its genome. The replicase proteins form membranous compartments in cells to facilitate replication, but little is known about their functional organization within these structures. W...

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Detalles Bibliográficos
Autores principales: Gomes, Rafael G. B., Isken, Olaf, Tautz, Norbert, McLauchlan, John, McCormick, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810661/
https://www.ncbi.nlm.nih.gov/pubmed/26719260
http://dx.doi.org/10.1128/JVI.01931-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810661/
https://www.ncbi.nlm.nih.gov/pubmed/26719260
http://dx.doi.org/10.1128/JVI.01931-15

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