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BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells
BACKGROUND: BAK (Bcl-2 homologous antagonist/killer) is a novel pro-apoptotic gene of the Bcl-2 family. It has been reported that gastric tumors have reduced BAK levels when compared with the normal mucosa. Moreover, mutations of the BAK gene have been identified in human gastrointestinal cancers, s...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC481072/ https://www.ncbi.nlm.nih.gov/pubmed/15248898 http://dx.doi.org/10.1186/1471-2407-4-33 |