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BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells

BACKGROUND: BAK (Bcl-2 homologous antagonist/killer) is a novel pro-apoptotic gene of the Bcl-2 family. It has been reported that gastric tumors have reduced BAK levels when compared with the normal mucosa. Moreover, mutations of the BAK gene have been identified in human gastrointestinal cancers, s...

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Detalles Bibliográficos
Autores principales: Tong, Qiang-Song, Zheng, Li-Duan, Wang, Liang, Liu, Jun, Qian, Wei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC481072/
https://www.ncbi.nlm.nih.gov/pubmed/15248898
http://dx.doi.org/10.1186/1471-2407-4-33