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Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function

The isthmic organizer (IsO) is a signaling center that specifies the correct and distinct embryonic development of the dopaminergic midbrain and serotonergic hindbrain. The IsO is a linear boundary between the two brain regions, emerging at around embryonic day 7-8 of murine embryonic development, t...

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Detalles Bibliográficos
Autores principales: Kouwenhoven, Willemieke M., Veenvliet, Jesse V., van Hooft, Johannes A., van der Heide, L. P., Smidt, Marten P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810741/
https://www.ncbi.nlm.nih.gov/pubmed/26879466
http://dx.doi.org/10.1242/bio.015032

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