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Cdk4 functions in multiple cell types to control Drosophila intestinal stem cell proliferation and differentiation
The proliferation of intestinal stem cells (ISCs) and differentiation of enteroblasts to form mature enteroendocrine cells and enterocytes in the Drosophila intestinal epithelium must be tightly regulated to maintain homeostasis. We show that genetic modulation of CyclinD/Cdk4 activity or mTOR-depen...
Autores principales: | Adlesic, Mojca, Frei, Christian, Frew, Ian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810749/ https://www.ncbi.nlm.nih.gov/pubmed/26879465 http://dx.doi.org/10.1242/bio.016584 |
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