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Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development

Pou domain transcription factor Pou4f2 is essential for the development of retinal ganglion cells (RGCs) in the vertebrate retina. A distant orthologue of Pou4f2 exists in the genome of the sea urchin (class Echinoidea) Strongylocentrotus purpuratus (SpPou4f1/2), yet the photosensory structure of se...

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Detalles Bibliográficos
Autores principales:	Mao, Chai-An, Agca, Cavit, Mocko-Strand, Julie A., Wang, Jing, Ullrich-Lüter, Esther, Pan, Ping, Wang, Steven W., Arnone, Maria Ina, Frishman, Laura J., Klein, William H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810862/ https://www.ncbi.nlm.nih.gov/pubmed/26962139 http://dx.doi.org/10.1098/rspb.2015.2978

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