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A rare aspect of Crohn's disease: Pulmonary involvement in a child
Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circula...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810924/ https://www.ncbi.nlm.nih.gov/pubmed/27076713 http://dx.doi.org/10.4103/0972-5229.175941 |
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author | Ongun, Ebru Atike Artan, Reha Bingol, Aysen Dursun, Oguz |
author_facet | Ongun, Ebru Atike Artan, Reha Bingol, Aysen Dursun, Oguz |
author_sort | Ongun, Ebru Atike |
collection | PubMed |
description | Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel disease activity; pulmonary involvement may be exarbecated. In the pediatric population, CD associated pulmonary involvement is very rare, mainly in the form of subclinical alterations and the data are limited mostly to case reports. Therefore, it is possibly overlooked since the diagnosis relies on suspicion. We represent a 5-year-old CD patient with previous bronchiolitis episodes that might have resulted from CD-associated pulmonary involvement; whom later developed severe pneumonia resulting in acute respiratory distress syndrome and bronchiectasia following a colectomy operation. |
format | Online Article Text |
id | pubmed-4810924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48109242016-04-13 A rare aspect of Crohn's disease: Pulmonary involvement in a child Ongun, Ebru Atike Artan, Reha Bingol, Aysen Dursun, Oguz Indian J Crit Care Med Case Report Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel disease activity; pulmonary involvement may be exarbecated. In the pediatric population, CD associated pulmonary involvement is very rare, mainly in the form of subclinical alterations and the data are limited mostly to case reports. Therefore, it is possibly overlooked since the diagnosis relies on suspicion. We represent a 5-year-old CD patient with previous bronchiolitis episodes that might have resulted from CD-associated pulmonary involvement; whom later developed severe pneumonia resulting in acute respiratory distress syndrome and bronchiectasia following a colectomy operation. Medknow Publications & Media Pvt Ltd 2016-02 /pmc/articles/PMC4810924/ /pubmed/27076713 http://dx.doi.org/10.4103/0972-5229.175941 Text en Copyright: © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Ongun, Ebru Atike Artan, Reha Bingol, Aysen Dursun, Oguz A rare aspect of Crohn's disease: Pulmonary involvement in a child |
title | A rare aspect of Crohn's disease: Pulmonary involvement in a child |
title_full | A rare aspect of Crohn's disease: Pulmonary involvement in a child |
title_fullStr | A rare aspect of Crohn's disease: Pulmonary involvement in a child |
title_full_unstemmed | A rare aspect of Crohn's disease: Pulmonary involvement in a child |
title_short | A rare aspect of Crohn's disease: Pulmonary involvement in a child |
title_sort | rare aspect of crohn's disease: pulmonary involvement in a child |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810924/ https://www.ncbi.nlm.nih.gov/pubmed/27076713 http://dx.doi.org/10.4103/0972-5229.175941 |
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