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A rare aspect of Crohn's disease: Pulmonary involvement in a child

Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circula...

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Autores principales: Ongun, Ebru Atike, Artan, Reha, Bingol, Aysen, Dursun, Oguz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810924/
https://www.ncbi.nlm.nih.gov/pubmed/27076713
http://dx.doi.org/10.4103/0972-5229.175941
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author Ongun, Ebru Atike
Artan, Reha
Bingol, Aysen
Dursun, Oguz
author_facet Ongun, Ebru Atike
Artan, Reha
Bingol, Aysen
Dursun, Oguz
author_sort Ongun, Ebru Atike
collection PubMed
description Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel disease activity; pulmonary involvement may be exarbecated. In the pediatric population, CD associated pulmonary involvement is very rare, mainly in the form of subclinical alterations and the data are limited mostly to case reports. Therefore, it is possibly overlooked since the diagnosis relies on suspicion. We represent a 5-year-old CD patient with previous bronchiolitis episodes that might have resulted from CD-associated pulmonary involvement; whom later developed severe pneumonia resulting in acute respiratory distress syndrome and bronchiectasia following a colectomy operation.
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spelling pubmed-48109242016-04-13 A rare aspect of Crohn's disease: Pulmonary involvement in a child Ongun, Ebru Atike Artan, Reha Bingol, Aysen Dursun, Oguz Indian J Crit Care Med Case Report Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel disease activity; pulmonary involvement may be exarbecated. In the pediatric population, CD associated pulmonary involvement is very rare, mainly in the form of subclinical alterations and the data are limited mostly to case reports. Therefore, it is possibly overlooked since the diagnosis relies on suspicion. We represent a 5-year-old CD patient with previous bronchiolitis episodes that might have resulted from CD-associated pulmonary involvement; whom later developed severe pneumonia resulting in acute respiratory distress syndrome and bronchiectasia following a colectomy operation. Medknow Publications & Media Pvt Ltd 2016-02 /pmc/articles/PMC4810924/ /pubmed/27076713 http://dx.doi.org/10.4103/0972-5229.175941 Text en Copyright: © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ongun, Ebru Atike
Artan, Reha
Bingol, Aysen
Dursun, Oguz
A rare aspect of Crohn's disease: Pulmonary involvement in a child
title A rare aspect of Crohn's disease: Pulmonary involvement in a child
title_full A rare aspect of Crohn's disease: Pulmonary involvement in a child
title_fullStr A rare aspect of Crohn's disease: Pulmonary involvement in a child
title_full_unstemmed A rare aspect of Crohn's disease: Pulmonary involvement in a child
title_short A rare aspect of Crohn's disease: Pulmonary involvement in a child
title_sort rare aspect of crohn's disease: pulmonary involvement in a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810924/
https://www.ncbi.nlm.nih.gov/pubmed/27076713
http://dx.doi.org/10.4103/0972-5229.175941
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