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Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria

Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Her...

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Autores principales: Shrestha, Gentle Sunder, Poudyal, Bishesh Sharma, Sedain, Gopal, Mahmud, Khandokar Imran, Acharya, Niranja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810925/
https://www.ncbi.nlm.nih.gov/pubmed/27076714
http://dx.doi.org/10.4103/0972-5229.175948
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author Shrestha, Gentle Sunder
Poudyal, Bishesh Sharma
Sedain, Gopal
Mahmud, Khandokar Imran
Acharya, Niranja
author_facet Shrestha, Gentle Sunder
Poudyal, Bishesh Sharma
Sedain, Gopal
Mahmud, Khandokar Imran
Acharya, Niranja
author_sort Shrestha, Gentle Sunder
collection PubMed
description Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Here, we present a rare combination of CVT presenting with intracerebral hemorrhage in a patient with PNH. High index of suspicion is needed to avoid misdiagnosis. Patient was successfully managed with anticoagulation therapy.
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spelling pubmed-48109252016-04-13 Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria Shrestha, Gentle Sunder Poudyal, Bishesh Sharma Sedain, Gopal Mahmud, Khandokar Imran Acharya, Niranja Indian J Crit Care Med Case Report Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Here, we present a rare combination of CVT presenting with intracerebral hemorrhage in a patient with PNH. High index of suspicion is needed to avoid misdiagnosis. Patient was successfully managed with anticoagulation therapy. Medknow Publications & Media Pvt Ltd 2016-02 /pmc/articles/PMC4810925/ /pubmed/27076714 http://dx.doi.org/10.4103/0972-5229.175948 Text en Copyright: © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Shrestha, Gentle Sunder
Poudyal, Bishesh Sharma
Sedain, Gopal
Mahmud, Khandokar Imran
Acharya, Niranja
Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
title Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
title_full Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
title_fullStr Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
title_full_unstemmed Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
title_short Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
title_sort cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810925/
https://www.ncbi.nlm.nih.gov/pubmed/27076714
http://dx.doi.org/10.4103/0972-5229.175948
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