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Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria
Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Her...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810925/ https://www.ncbi.nlm.nih.gov/pubmed/27076714 http://dx.doi.org/10.4103/0972-5229.175948 |
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author | Shrestha, Gentle Sunder Poudyal, Bishesh Sharma Sedain, Gopal Mahmud, Khandokar Imran Acharya, Niranja |
author_facet | Shrestha, Gentle Sunder Poudyal, Bishesh Sharma Sedain, Gopal Mahmud, Khandokar Imran Acharya, Niranja |
author_sort | Shrestha, Gentle Sunder |
collection | PubMed |
description | Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Here, we present a rare combination of CVT presenting with intracerebral hemorrhage in a patient with PNH. High index of suspicion is needed to avoid misdiagnosis. Patient was successfully managed with anticoagulation therapy. |
format | Online Article Text |
id | pubmed-4810925 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48109252016-04-13 Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria Shrestha, Gentle Sunder Poudyal, Bishesh Sharma Sedain, Gopal Mahmud, Khandokar Imran Acharya, Niranja Indian J Crit Care Med Case Report Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Here, we present a rare combination of CVT presenting with intracerebral hemorrhage in a patient with PNH. High index of suspicion is needed to avoid misdiagnosis. Patient was successfully managed with anticoagulation therapy. Medknow Publications & Media Pvt Ltd 2016-02 /pmc/articles/PMC4810925/ /pubmed/27076714 http://dx.doi.org/10.4103/0972-5229.175948 Text en Copyright: © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Shrestha, Gentle Sunder Poudyal, Bishesh Sharma Sedain, Gopal Mahmud, Khandokar Imran Acharya, Niranja Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
title | Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
title_full | Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
title_fullStr | Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
title_full_unstemmed | Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
title_short | Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
title_sort | cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810925/ https://www.ncbi.nlm.nih.gov/pubmed/27076714 http://dx.doi.org/10.4103/0972-5229.175948 |
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