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Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit

Renal cell carcinoma (RCC) has unusual presentation affecting elderly males with a smoking history. The incidence of RCC varies while the incidence of spread of RCC to the clivus is rare. The typicality of RCC presentation includes hematuria, flank pain, and a palpable flank mass; however, RCC can a...

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Autores principales: Okudo, Jerome, Anusim, Nwabundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811068/
https://www.ncbi.nlm.nih.gov/pubmed/27110412
http://dx.doi.org/10.1155/2016/9184501
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author Okudo, Jerome
Anusim, Nwabundo
author_facet Okudo, Jerome
Anusim, Nwabundo
author_sort Okudo, Jerome
collection PubMed
description Renal cell carcinoma (RCC) has unusual presentation affecting elderly males with a smoking history. The incidence of RCC varies while the incidence of spread of RCC to the clivus is rare. The typicality of RCC presentation includes hematuria, flank pain, and a palpable flank mass; however, RCC can also present with clival metastasis. The unique path of the abducens nerve in the clivus makes it susceptible to damage in metastasis. We report a case of a 54-year-old African American female that was evaluated for back pain, weakness, numbness, and tingling of bilateral lower extremities and subsequently disconjugate gaze and diplopia. Brain MRI confirmed metastasis to the clivus. She was started on radiotherapy and was planned for chemotherapy and transfer to a nursing home. When a patient presents with sudden unusual cranial nerve pathology, the possibility of metastatic RCC should be sought.
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spelling pubmed-48110682016-04-24 Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit Okudo, Jerome Anusim, Nwabundo Case Rep Neurol Med Case Report Renal cell carcinoma (RCC) has unusual presentation affecting elderly males with a smoking history. The incidence of RCC varies while the incidence of spread of RCC to the clivus is rare. The typicality of RCC presentation includes hematuria, flank pain, and a palpable flank mass; however, RCC can also present with clival metastasis. The unique path of the abducens nerve in the clivus makes it susceptible to damage in metastasis. We report a case of a 54-year-old African American female that was evaluated for back pain, weakness, numbness, and tingling of bilateral lower extremities and subsequently disconjugate gaze and diplopia. Brain MRI confirmed metastasis to the clivus. She was started on radiotherapy and was planned for chemotherapy and transfer to a nursing home. When a patient presents with sudden unusual cranial nerve pathology, the possibility of metastatic RCC should be sought. Hindawi Publishing Corporation 2016 2016-03-15 /pmc/articles/PMC4811068/ /pubmed/27110412 http://dx.doi.org/10.1155/2016/9184501 Text en Copyright © 2016 J. Okudo and N. Anusim. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Okudo, Jerome
Anusim, Nwabundo
Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit
title Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit
title_full Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit
title_fullStr Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit
title_full_unstemmed Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit
title_short Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit
title_sort unusual spread of renal cell carcinoma to the clivus with cranial nerve deficit
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811068/
https://www.ncbi.nlm.nih.gov/pubmed/27110412
http://dx.doi.org/10.1155/2016/9184501
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