Cargando…

A Porcine Anterior Segment Perfusion and Transduction Model With Direct Visualization of the Trabecular Meshwork

PURPOSE: To establish a consistent and affordable, high quality porcine anterior segment perfusion and transduction model that allows direct visualization of the trabecular meshwork. METHODS: Porcine anterior segments were cultured within 2 hours of death by removing lens and uvea and securing in a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Loewen, Ralitsa T., Roy, Pritha, Park, Daniel B., Jensen, Adrianna, Scott, Gordon, Cohen-Karni, Devora, Fautsch, Michael P., Schuman, Joel S., Loewen, Nils A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2016
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811178/ https://www.ncbi.nlm.nih.gov/pubmed/27002293 http://dx.doi.org/10.1167/iovs.15-18125

Ejemplares similares

Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells
por: MacDonald, William W., et al.
Publicado: (2022)

Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model
por: Dang, Yalong, et al.
Publicado: (2017)

Tissue-engineered anterior segment eye cultures demonstrate hallmarks of conventional organ culture
por: Waxman, Susannah, et al.
Publicado: (2022)

Quantification of Focal Outflow Enhancement Using Differential Canalograms
por: Loewen, Ralitsa T., et al.
Publicado: (2016)

Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork
por: Aktas, Zeynep, et al.
Publicado: (2018)

High-Resolution, Three-Dimensional Reconstruction of the Outflow Tract Demonstrates Segmental Differences in Cleared Eyes
por: Waxman, Susannah, et al.
Publicado: (2018)

Structure–Function Changes of the Porcine Distal Outflow Tract in Response to Nitric Oxide
por: Waxman, Susannah, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway
por: Wang, Yiwen, et al.
Publicado: (2019)

A Porcine Organ-Culture Glaucoma Model Mimicking Trabecular Meshwork Damage Using Oxidative Stress
por: Snider, Eric J., et al.
Publicado: (2021)

Morphology of the Trabecular Meshwork and Schlemm's Canal in Posner-Schlossman Syndrome
por: Yan, Xiaoqin, et al.
Publicado: (2022)

Comparison of a second-generation trabecular bypass (iStent inject) to ab interno trabeculectomy (Trabectome) by exact matching
por: Al Yousef, Yousef, et al.
Publicado: (2020)

Inhibition of TGF-β2–Induced Trabecular Meshwork Fibrosis by Pirfenidone
por: Zhu, Xiaofeng, et al.
Publicado: (2023)

Differential Canalograms Detect Outflow Changes from Trabecular Micro-Bypass Stents and Ab Interno Trabeculectomy
por: Parikh, Hardik A., et al.
Publicado: (2016)

BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork
por: Hernandez, Humberto, et al.
Publicado: (2018)

Estimating Human Trabecular Meshwork Stiffness by Numerical Modeling and Advanced OCT Imaging
por: Wang, Ke, et al.
Publicado: (2017)

Phenotypic and Functional Alterations in Tunneling Nanotubes Formed by Glaucomatous Trabecular Meshwork Cells
por: Sun, Ying Ying, et al.
Publicado: (2019)

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells
por: Keller, Kate E., et al.
Publicado: (2017)

Effects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure
por: Tan, Junka, et al.
Publicado: (2018)

The Molecular Processes in the Trabecular Meshwork After Exposure to Corticosteroids and in Corticosteroid-Induced Ocular Hypertension
por: Liesenborghs, Ilona, et al.
Publicado: (2020)

HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork
por: Bermudez, Jaclyn Y., et al.
Publicado: (2016)

Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation
por: Sun, Ying Ying, et al.
Publicado: (2019)

Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype
por: Dhamodaran, Kamesh, et al.
Publicado: (2020)

Osthole Reduces Mouse IOP Associated With Ameliorating Extracellular Matrix Expression of Trabecular Meshwork Cell
por: Fan, Yuchen, et al.
Publicado: (2020)

Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork
por: Kasetti, Ramesh B., et al.
Publicado: (2016)

Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork
por: Hernandez, Humberto, et al.
Publicado: (2017)

TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology
por: Ashok, Ajay, et al.
Publicado: (2020)

Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases
por: Brazile, Bryn L., et al.
Publicado: (2020)

Growth Differentiation Factor-15–Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells
por: Muralidharan, Arumugam Ramachandran, et al.
Publicado: (2016)

Expression of mRNAs, miRNAs, and lncRNAs in Human Trabecular Meshwork Cells Upon Mechanical Stretch
por: Youngblood, Hannah, et al.
Publicado: (2020)

Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells
por: Ho, Leona T. Y., et al.
Publicado: (2018)

The Effect of Dietary Vitamin K1 Supplementation on Trabecular Meshwork and Retina in a Chronic Ocular Hypertensive Rat Model
por: Deng, Chaohua, et al.
Publicado: (2020)

Dexamethasone and Glucocorticoid-Induced Matrix Temporally Modulate Key Integrins, Caveolins, Contractility, and Stiffness in Human Trabecular Meshwork Cells
por: Yemanyi, Felix, et al.
Publicado: (2020)

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice
por: De Groef, Lies, et al.
Publicado: (2016)

Crosslinked Extracellular Matrix Stiffens Human Trabecular Meshwork Cells Via Dysregulating β-catenin and YAP/TAZ Signaling Pathways
por: Yemanyi, Felix, et al.
Publicado: (2020)

TGF-β2 Promotes Oxidative Stress in Human Trabecular Meshwork Cells by Selectively Enhancing NADPH Oxidase 4 Expression
por: Rao, Vidhya R., et al.
Publicado: (2021)

Reduced Pulsatile Trabecular Meshwork Motion in Eyes With Primary Open Angle Glaucoma Using Phase-Sensitive Optical Coherence Tomography
por: Gao, Kai, et al.
Publicado: (2020)

Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma
por: Zhu, Wei, et al.
Publicado: (2017)

Activation of αvβ3 Integrin Alters Fibronectin Fibril Formation in Human Trabecular Meshwork Cells in a ROCK-Independent Manner
por: Filla, Mark S., et al.
Publicado: (2019)

Lysophosphatidic Acid and IL-6 Trans-signaling Interact via YAP/TAZ and STAT3 Signaling Pathways in Human Trabecular Meshwork Cells
por: Yemanyi, Felix, et al.
Publicado: (2020)

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma
por: Sui, Shangru, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_05fmjtrcq06kt5td4sekh5nkk0