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Mechanisms Behind the Resistance to Trastuzumab in HER2-Amplified Breast Cancer and Strategies to Overcome It

The introduction of trastuzumab therapy markedly improved the poor prognosis associated with HER2-amplified breast cancers. Despite this, the presence of primary and acquired resistance to trastuzumab treatment remains a significant common challenge. The identification of resistance mechanisms and t...

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Detalles Bibliográficos
Autores principales:	Luque-Cabal, María, García-Teijido, Paula, Fernández-Pérez, Yolanda, Sánchez-Lorenzo, Luisa, Palacio-Vázquez, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811269/ https://www.ncbi.nlm.nih.gov/pubmed/27042153 http://dx.doi.org/10.4137/CMO.S34537

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