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Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P(2) to mediate tumour cell permeabilisation

Cationic antimicrobial peptides (CAPs), including taxonomically diverse defensins, are innate defense molecules that display potent antimicrobial and immunomodulatory activities. Specific CAPs have also been shown to possess anticancer activities; however, their mechanisms of action are not well def...

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Detalles Bibliográficos
Autores principales:	Phan, Thanh Kha, Lay, Fung T., Poon, Ivan K.H., Hinds, Mark G., Kvansakul, Marc, Hulett, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811302/ https://www.ncbi.nlm.nih.gov/pubmed/26657293

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