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Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk

BACKGROUND: Modeling studies using hypothetical polygenic risk data can be an efficient tool for investigating the effectiveness of downstream applications such as targeting interventions to risk groups to justify whether empirical investigation is warranted. We investigated the assumptions underlyi...

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Detalles Bibliográficos
Autores principales:	Kundu, Suman, Kers, Jannigje G., Janssens, A. Cecile J. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811433/ https://www.ncbi.nlm.nih.gov/pubmed/27023073 http://dx.doi.org/10.1371/journal.pone.0152359

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