ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

Programmed cell death 4 (PDCD4) is a tumour suppressor implicated in cancer development and progression and was recently identified as a repressor of cap-independent translation of specific genes involved in the regulation of apoptosis. We show that the RNA-binding protein HuR binds to the PDCD4 3′U...

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Detalles Bibliográficos
Autores principales: Liwak-Muir, Urszula, Dobson, Christine C., Naing, Thet, Wylie, Quinlan, Chehade, Lucia, Baird, Stephen D., Chakraborty, Pranesh K., Holcik, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811471/
https://www.ncbi.nlm.nih.gov/pubmed/26595526

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