Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma

AIMS: Antibodies targeting the checkpoint molecules programmed cell death 1 (PD-1) and its ligand PD-L1 are emerging cancer therapeutics. We systematically investigated PD-1 and PD-L1 expression patterns in the poor-prognosis tumor entity high-grade serous ovarian carcinoma. METHODS: PD-1 and PD-L1...

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Detalles Bibliográficos
Autores principales: Darb-Esfahani, Silvia, Kunze, Catarina Alisa, Kulbe, Hagen, Sehouli, Jalid, Wienert, Stephan, Lindner, Judith, Budczies, Jan, Bockmayr, Michael, Dietel, Manfred, Denkert, Carsten, Braicu, Ioana, Jöhrens, Korinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811475/
https://www.ncbi.nlm.nih.gov/pubmed/26625204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811475/
https://www.ncbi.nlm.nih.gov/pubmed/26625204

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