Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma

Phospholipase C epsilon 1 (PLCE1) is a susceptibility gene in esophageal squamous cell carcinoma (ESCC). Nevertheless, the role of PLCE1 in ESCC tumorigenesis has not been elucidated. In this study, we determined the function of PLCE1 and its regulatory microRNA (miRNA) in ESCC. PLCE1 protein was ex...

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Detalles Bibliográficos
Autores principales: Cui, Xiao-Bin, Li, Su, Li, Ting-Ting, Peng, Hao, Jin, Ting-Ting, Zhang, Shu-Mao, Liu, Chun-Xia, Yang, Lan, Shen, Yao-Yuan, Li, Shu-Gang, Li, Na, Li, Yong, Hu, Jian-Ming, Jiang, Jin-Fang, Suo, Jing, Qi, Yan, Liang, Wei-Hua, Wang, Liang-Hai, Dang, Hong-Wei, Li, Li, Cao, Wei-Wei, Wei, Yutao, Yin, Laibo, Wu, Chuan-Yue, Yuan, Xiang-Lin, Zhou, Hong, Zheng, Yu, Chen, Yun-Zhao, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811497/
https://www.ncbi.nlm.nih.gov/pubmed/26657507

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