Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer

Metastasis causes a large number of deaths among esophageal cancer patients. The activation of RAF family proteins elevates tumor metastasis and proliferation. In screen targeting the RAF protein, we identified that Griffipavixanthone (GPX), a dimeric xanthone isolated from Garcinia esculenta, is a...

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Detalles Bibliográficos
Autores principales: Ding, Zhijie, Lao, Yuanzhi, Zhang, Hong, Fu, Wenwei, Zhu, Lunlun, Tan, Hongsheng, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811500/
https://www.ncbi.nlm.nih.gov/pubmed/26646323

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