Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

Accurate assessment of neuroblastoma outcome prediction remains challenging. Therefore, this study aims at establishing novel prognostic tumor DNA methylation biomarkers. In total, 396 low- and high-risk primary tumors were analyzed, of which 87 were profiled using methyl-CpG-binding domain (MBD) se...

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Detalles Bibliográficos
Autores principales: Decock, Anneleen, Ongenaert, Maté, Cannoodt, Robrecht, Verniers, Kimberly, De Wilde, Bram, Laureys, Geneviève, Van Roy, Nadine, Berbegall, Ana P., Bienertova-Vasku, Julie, Bown, Nick, Clément, Nathalie, Combaret, Valérie, Haber, Michelle, Hoyoux, Claire, Murray, Jayne, Noguera, Rosa, Pierron, Gaelle, Schleiermacher, Gudrun, Schulte, Johannes H., Stallings, Ray L., Tweddle, Deborah A., De Preter, Katleen, Speleman, Frank, Vandesompele, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811509/
https://www.ncbi.nlm.nih.gov/pubmed/26646589

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