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Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis
There is abundant epidemiological evidence that heavy alcohol intake contributes to hepatocellular carcinoma (HCC) development. Previous reports indicated that connexin 32 (Cx32), which is a major hepatocyte gap junction protein, is down-regulated in chronic liver disease and has a protective role i...
Autores principales: | Kato, Hiroyuki, Naiki-Ito, Aya, Naiki, Taku, Suzuki, Shugo, Yamashita, Yoriko, Sato, Shinya, Sagawa, Hiroyuki, Kato, Akihisa, Kuno, Toshiya, Takahashi, Satoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811513/ https://www.ncbi.nlm.nih.gov/pubmed/26655499 |
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