MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth

Angiogenesis is a key process occurring under both physiological and pathological conditions and is a hallmark of cancer. We have recently demonstrated that the extracellular matrix (ECM) molecule MULTIMERIN2 exerts an angiostatic function through the binding to VEGF-A. In this study we identify the...

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Detalles Bibliográficos
Autores principales: Colladel, Roberta, Pellicani, Rosanna, Andreuzzi, Eva, Paulitti, Alice, Tarticchio, Giulia, Todaro, Federico, Colombatti, Alfonso, Mongiat, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811514/
https://www.ncbi.nlm.nih.gov/pubmed/26655500

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