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Loss of 11βHSD1 enhances glycolysis, facilitates intrahepatic metastasis, and indicates poor prognosis in hepatocellular carcinoma
11Beta-hydroxysteroid dehydrogenase type 1 (11βHSD1), converting glucocorticoids from hormonally inactive cortisone to active cortisol, plays an essential role in glucose homeostasis. Accumulating evidence suggests that enhanced glycolytic activity is closely associated with postoperative recurrence...
Autores principales: | Liu, Xu, Tan, Xiao-long, Xia, Meng, Wu, Chao, Song, Jia, Wu, Jing-jing, Laurence, Arian, Xie, Qing-guo, Zhang, Ming-zhi, Liang, Hui-fang, Zhang, Bi-xiang, Chen, Xiao-ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811515/ https://www.ncbi.nlm.nih.gov/pubmed/26700460 |
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