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Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage
Acute myeloid leukemia (AML) cells induce, in vitro, NK cell abnormalities (NKCAs) including apoptosis and activating receptor down-regulation. The potential negative impact of AML cells on the therapeutic efficacy of NK cell-based strategies prompted us to analyze the mechanisms underlying NKCAs an...
Autores principales: | Arriga, Roberto, Caratelli, Sara, Coppola, Andrea, Spagnoli, Giulio Cesare, Venditti, Adriano, Amadori, Sergio, Lanzilli, Giulia, Lauro, Davide, Palomba, Patrizia, Sconocchia, Tommaso, Del Principe, Maria Ilaria, Maurillo, Luca, Buccisano, Francesco, Capuani, Barbara, Ferrone, Soldano, Sconocchia, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811516/ https://www.ncbi.nlm.nih.gov/pubmed/26655503 |
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