Cargando…

Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer

OBJECTIVES: MAP4K5 plays an important role in regulating a range of cellular responses and is involved in Wnt signaling in hematopoietic cells. However, its functions in human malignancies have not been studied. The major objectives of this study are to examine the expression, functions and clinical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Oliver H., Azizian, Nancy, Guo, Ming, Capello, Michela, Deng, Defeng, Zang, Fenglin, Fry, Jason, Katz, Matthew H., Fleming, Jason B., Lee, Jeffrey E., Wolff, Robert A., Hanash, Samir, Wang, Huamin, Maitra, Anirban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811546/ https://www.ncbi.nlm.nih.gov/pubmed/27023625 http://dx.doi.org/10.1371/journal.pone.0152300

Ejemplares similares

Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor
por: Kailass, Karishma, et al.
Publicado: (2019)

CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop
por: Chen, Yihui, et al.
Publicado: (2021)

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma
por: Liu, Qingqing, et al.
Publicado: (2017)

Plasma-Derived Extracellular Vesicles Convey Protein Signatures That Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas
por: Fahrmann, Johannes F., et al.
Publicado: (2020)

Tumor-Associated and Systemic Autoimmunity in Pre-Clinical Breast Cancer among Post-Menopausal Women
por: Parks, Christine G., et al.
Publicado: (2023)

Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity
por: Capello, Michela, et al.
Publicado: (2019)

Computed Tomography–Based Biomarker Outcomes in a Prospective Trial of Preoperative FOLFIRINOX and Chemoradiation for Borderline Resectable Pancreatic Cancer
por: Koay, Eugene J., et al.
Publicado: (2019)

A plasma protein derived TGFβ signature is a prognostic indicator in triple negative breast cancer
por: Katayama, Hiroyuki, et al.
Publicado: (2019)

A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer
por: Fahrmann, Johannes F, et al.
Publicado: (2018)

Comparative Analyses of the Clinicopathologic Features of Short-Term and Long-Term Survivors of Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreatoduodenectomy
por: Liang, Tom Z., et al.
Publicado: (2023)

Prognosticators for Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Therapy and Pancreatectomy
por: Tong, Yi Tat, et al.
Publicado: (2023)

Immune-Complexome Analysis Identifies Immunoglobulin-Bound Biomarkers That Predict the Response to Chemotherapy of Pancreatic Cancer Patients
por: Mandili, Giorgia, et al.
Publicado: (2020)

Integrative Analysis of Novel Metabolic Subtypes in Pancreatic Cancer Fosters New Prognostic Biomarkers
por: Follia, Laura, et al.
Publicado: (2019)

Impact of KRAS Mutations and Co-mutations on Clinical Outcomes in Pancreatic Ductal Adenocarcinoma
por: Yousef, Abdelrahman, et al.
Publicado: (2023)

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma
por: Kang, Ya’an, et al.
Publicado: (2022)

Quantitative imaging to evaluate malignant potential of IPMNs
por: Hanania, Alexander N., et al.
Publicado: (2016)

Squamoid Cystosis of Pancreatic Ducts: A Variant of a Newly-Described Cystic Lesion, with Evidence for an Obstructive Etiology
por: Foo, Wai Chin, et al.
Publicado: (2014)

Imaging‐based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy
por: Amer, Ahmed M., et al.
Publicado: (2018)

Recent insights into the biology of pancreatic cancer
por: Yao, Wantong, et al.
Publicado: (2020)

Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer
por: Wang, Charles X., et al.
Publicado: (2022)

SMAD4 Regulates Cell Motility through Transcription of N-Cadherin in Human Pancreatic Ductal Epithelium
por: Kang, Ya'an, et al.
Publicado: (2014)

Hepatocyte Nuclear Factor 1A (HNF1A) as a Possible Tumor Suppressor in Pancreatic Cancer
por: Luo, Zhaofan, et al.
Publicado: (2015)

Predictive Modeling for Voxel-Based Quantification of Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma (PDAC): A Multi-Institutional Study
por: Zaid, Mohamed, et al.
Publicado: (2020)

Syndecan1 is a critical mediator of macropinocytosis in pancreatic cancer
por: Yao, Wantong, et al.
Publicado: (2019)

Serum CA 19-9 as a Marker of Resectability and Survival in Patients with Potentially Resectable Pancreatic Cancer Treated with Neoadjuvant Chemoradiation
por: Katz, Matthew H. G., et al.
Publicado: (2010)

Mapping mountains
por: Capello, Ernesto
Publicado: (2020)

PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer
por: Douglas, Julia E., et al.
Publicado: (2022)

Prevalence of extra-pancreatic cysts in patients with cystic pancreatic lesions detected by endoscopic ultrasound
por: Bektas, Mehmet, et al.
Publicado: (2015)

A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms
por: Barua, Souptik, et al.
Publicado: (2018)

Phase I Trial of Consolidative Radiotherapy with Concurrent Bevacizumab, Erlotinib and Capecitabine for Unresectable Pancreatic Cancer
por: Chadha, Awalpreet S., et al.
Publicado: (2016)

Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia
por: Wang, Hua, et al.
Publicado: (2023)

Molecular Characteristics of Pancreatic Ductal Adenocarcinoma
por: Ottenhof, Niki A., et al.
Publicado: (2011)

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts
por: Hoover, Malachia, et al.
Publicado: (2016)

Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells
por: Du, Rong, et al.
Publicado: (2021)

The role of stromal cancer-associated fibroblasts in pancreatic cancer
por: von Ahrens, Dagny, et al.
Publicado: (2017)

Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53
por: Swidnicka-Siergiejko, A K, et al.
Publicado: (2017)

Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis
por: Chang, Zhe, et al.
Publicado: (2014)

Lung cancer susceptibility beyond smoking history: opportunities and challenges
por: Hanash, Samir
Publicado: (2022)

ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma
por: Kim, Michael P., et al.
Publicado: (2011)

Regression of Stage IV Pancreatic Cancer to Curative Surgery and Introduction of a Novel Ex-Vivo Chemosensitivity Assay
por: Rios Perez, Mayrim V, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7v5ibh9h7v8n8ooo53347bd4ur