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TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair

BACKGROUND: Impaired remyelination of demyelinated axons is a major cause of neurological disability. In inflammatory demyelinating disease of the central nervous system (CNS), although remyelination does happen, it is often incomplete, resulting in poor clinical recovery. Poly-IC a known TLR3 agoni...

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Detalles Bibliográficos
Autores principales: Natarajan, Chandramohan, Yao, Song-Yi, Sriram, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811556/
https://www.ncbi.nlm.nih.gov/pubmed/27022724
http://dx.doi.org/10.1371/journal.pone.0152163