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Colorectal Cancer Genetic Heterogeneity Delineated by Multi-Region Sequencing

Intratumor heterogeneity (ITH) leads to an underestimation of the mutational landscape portrayed by a single needle biopsy and consequently affects treatment precision. The extent of colorectal cancer (CRC) genetic ITH is not well understood in Chinese patients. Thus, we conducted deep sequencing by...

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Detalles Bibliográficos
Autores principales:	Lu, You-Wang, Zhang, Hui-Feng, Liang, Rui, Xie, Zhen-Rong, Luo, Hua-You, Zeng, Yu-Jian, Xu, Yu, Wang, La-Mei, Kong, Xiang-Yang, Wang, Kun-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811559/ https://www.ncbi.nlm.nih.gov/pubmed/27023146 http://dx.doi.org/10.1371/journal.pone.0152673

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