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Comparative Analysis of Matrix Metalloproteinase Family Members Reveals That MMP9 Predicts Survival and Response to Temozolomide in Patients with Primary Glioblastoma

BACKGROUND: Glioblastoma multiform (GBM) is the most common malignant primary brain tumor in adults. Radiotherapy plus concomitant and adjuvant TMZ chemotherapy is the current standard of care for patients with GBM. Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, are key...

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Detalles Bibliográficos
Autores principales:	Li, Qingbin, Chen, Baoshi, Cai, Jinquan, Sun, Ying, Wang, Guangzhi, Li, Yongli, Li, Ruiyan, Feng, Yan, Han, Bo, Li, Jianlong, Tian, Yu, Yi, Liye, Jiang, Chuanlu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811585/ https://www.ncbi.nlm.nih.gov/pubmed/27022952 http://dx.doi.org/10.1371/journal.pone.0151815

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