Role of Nrf2, HO-1 and GSH in Neuroblastoma Cell Resistance to Bortezomib

The activation of Nrf2 has been demonstrated to play a crucial role in cancer cell resistance to different anticancer therapies. The inhibition of proteasome activity has been proposed as a chemosensitizing therapy but the activation of Nrf2 could reduce its efficacy. Using the highly chemoresistant...

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Detalles Bibliográficos
Autores principales: Furfaro, A. L., Piras, S., Domenicotti, C., Fenoglio, D., De Luigi, A., Salmona, M., Moretta, L., Marinari, U. M., Pronzato, M. A., Traverso, N., Nitti, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811586/
https://www.ncbi.nlm.nih.gov/pubmed/27023064
http://dx.doi.org/10.1371/journal.pone.0152465

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