Bacillus bombysepticus α-Toxin Binding to G Protein-Coupled Receptor Kinase 2 Regulates cAMP/PKA Signaling Pathway to Induce Host Death

Bacterial pathogens and their toxins target host receptors, leading to aberrant behavior or host death by changing signaling events through subversion of host intracellular cAMP level. This is an efficient and widespread mechanism of microbial pathogenesis. Previous studies describe toxins that incr...

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Detalles Bibliográficos
Autores principales: Lin, Ping, Cheng, Tingcai, Ma, Sanyuan, Gao, Junping, Jin, Shengkai, Jiang, Liang, Xia, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811588/
https://www.ncbi.nlm.nih.gov/pubmed/27022742
http://dx.doi.org/10.1371/journal.ppat.1005527

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