Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study

Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among...

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Detalles Bibliográficos
Autores principales: Stevens, Vanessa W., Thurm, Cary, Schwab, Elyse M., Kronman, Matthew P., Gerber, Jeffrey S., Shah, Samir S., Newland, Jason G., Courter, Joshua, Parker, Sarah, Brogan, Thomas V., Hersh, Adam L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811838/
https://www.ncbi.nlm.nih.gov/pubmed/26972929
http://dx.doi.org/10.1007/s40121-016-0105-2
Descripción
Sumario:Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.

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