Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study

Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among...

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Autores principales: Stevens, Vanessa W., Thurm, Cary, Schwab, Elyse M., Kronman, Matthew P., Gerber, Jeffrey S., Shah, Samir S., Newland, Jason G., Courter, Joshua, Parker, Sarah, Brogan, Thomas V., Hersh, Adam L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811838/
https://www.ncbi.nlm.nih.gov/pubmed/26972929
http://dx.doi.org/10.1007/s40121-016-0105-2
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author Stevens, Vanessa W.
Thurm, Cary
Schwab, Elyse M.
Kronman, Matthew P.
Gerber, Jeffrey S.
Shah, Samir S.
Newland, Jason G.
Courter, Joshua
Parker, Sarah
Brogan, Thomas V.
Hersh, Adam L.
author_facet Stevens, Vanessa W.
Thurm, Cary
Schwab, Elyse M.
Kronman, Matthew P.
Gerber, Jeffrey S.
Shah, Samir S.
Newland, Jason G.
Courter, Joshua
Parker, Sarah
Brogan, Thomas V.
Hersh, Adam L.
author_sort Stevens, Vanessa W.
collection PubMed
description Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.
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spelling pubmed-48118382016-04-09 Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study Stevens, Vanessa W. Thurm, Cary Schwab, Elyse M. Kronman, Matthew P. Gerber, Jeffrey S. Shah, Samir S. Newland, Jason G. Courter, Joshua Parker, Sarah Brogan, Thomas V. Hersh, Adam L. Infect Dis Ther Original Research Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children’s hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship. Springer Healthcare 2016-03-14 2016-03 /pmc/articles/PMC4811838/ /pubmed/26972929 http://dx.doi.org/10.1007/s40121-016-0105-2 Text en © The Author(s) 2016 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Research
Stevens, Vanessa W.
Thurm, Cary
Schwab, Elyse M.
Kronman, Matthew P.
Gerber, Jeffrey S.
Shah, Samir S.
Newland, Jason G.
Courter, Joshua
Parker, Sarah
Brogan, Thomas V.
Hersh, Adam L.
Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study
title Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study
title_full Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study
title_fullStr Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study
title_full_unstemmed Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study
title_short Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study
title_sort use of concomitant antibiotics during treatment for clostridium difficile infection (cdi) in pediatric inpatients: an observational cohort study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811838/
https://www.ncbi.nlm.nih.gov/pubmed/26972929
http://dx.doi.org/10.1007/s40121-016-0105-2
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