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Wnt/β-Catenin Regulates the Activity of Epiprofin/Sp6, SHH, FGF, and BMP to Coordinate the Stages of Odontogenesis
Background: We used an in vitro tooth development model to investigate the effects of overactivation of the Wnt/β-catenin pathway during odontogenesis by bromoindirubin oxime reagent (BIO), a specific inhibitor of GSK-3 activity. Results: Overactivating the Wnt/β-catenin pathway at tooth initiation...
Autores principales: | Aurrekoetxea, Maitane, Irastorza, Igor, García-Gallastegui, Patricia, Jiménez-Rojo, Lucia, Nakamura, Takashi, Yamada, Yoshihiko, Ibarretxe, Gaskon, Unda, Fernando J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811915/ https://www.ncbi.nlm.nih.gov/pubmed/27066482 http://dx.doi.org/10.3389/fcell.2016.00025 |
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