Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with an enhanced risk for liver and cardiovascular diseases and mortality. NAFLD can progress from simple hepatic steatosis to non-alcoholic steatohepatitis (NASH). However, the mechanisms...

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Detalles Bibliográficos
Autores principales: Schröder, Torsten, Kucharczyk, David, Bär, Florian, Pagel, René, Derer, Stefanie, Jendrek, Sebastian Torben, Sünderhauf, Annika, Brethack, Ann-Kathrin, Hirose, Misa, Möller, Steffen, Künstner, Axel, Bischof, Julia, Weyers, Imke, Heeren, Jörg, Koczan, Dirk, Schmid, Sebastian Michael, Divanovic, Senad, Giles, Daniel Aaron, Adamski, Jerzy, Fellermann, Klaus, Lehnert, Hendrik, Köhl, Jörg, Ibrahim, Saleh, Sina, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812012/
https://www.ncbi.nlm.nih.gov/pubmed/27069868
http://dx.doi.org/10.1016/j.molmet.2016.01.010

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