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Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGFβ, and extracellular matrix

The bipotential differentiation of liver progenitor cells underlies liver development and bile duct formation as well as liver regeneration and disease. TGFβ and Notch signaling are known to play important roles in the liver progenitor specification process and tissue morphogenesis. However, the com...

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Detalles Bibliográficos
Autores principales: Kaylan, Kerim B., Ermilova, Viktoriya, Yada, Ravi Chandra, Underhill, Gregory H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812246/
https://www.ncbi.nlm.nih.gov/pubmed/27025873
http://dx.doi.org/10.1038/srep23490