Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model

Type 1 diabetes is an autoimmune disease in which insulin-producing pancreatic islet β cells are the target of self-reactive B and T cells. T cells reactive with epitopes derived from insulin and/or IGRP are critical for the initiation and maintenance of disease, but T cells reactive with other isle...

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Detalles Bibliográficos
Autores principales: Yu, Cailin, Burns, Jeremy C., Robinson, William H., Utz, Paul J., Ho, Peggy P., Steinman, Lawrence, Frey, Alan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812430/
https://www.ncbi.nlm.nih.gov/pubmed/27069933
http://dx.doi.org/10.1155/2016/9083103

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