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Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection

Bacterial infections are common but have become increasingly resistant to drugs. The aim of the present study was to examine the combined treatment of traditional Chinese and Western medicine in 30 cases of pulmonary infection with multidrug resistant Acinetobacter baumannii. Patients were divided i...

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Autores principales: PAN, TAO, LIU, XIAOYUN, XIANG, SHOUGUI, JI, WENLI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812438/
https://www.ncbi.nlm.nih.gov/pubmed/27073447
http://dx.doi.org/10.3892/etm.2016.3051
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author PAN, TAO
LIU, XIAOYUN
XIANG, SHOUGUI
JI, WENLI
author_facet PAN, TAO
LIU, XIAOYUN
XIANG, SHOUGUI
JI, WENLI
author_sort PAN, TAO
collection PubMed
description Bacterial infections are common but have become increasingly resistant to drugs. The aim of the present study was to examine the combined treatment of traditional Chinese and Western medicine in 30 cases of pulmonary infection with multidrug resistant Acinetobacter baumannii. Patients were divided into groups A and B according to drug treatments. Cefoperazone or sulbactam and tanreqing were administered in group A, and cefoperazone or sulbactam in group B. The curative effect and prognosis of the two groups were recorded and the remaining treatments were performed routinely in the clinic. For the combined therapy group, which was administered sulperazone and tanreqing, 8 patients were recovered, 6 patients had significant effects, 3 patients exhibited some improvement and 1 patient had no response. One of the patients did not survive after 28 days. By contrast, there were 4 patients that were successfully treated, 3 patients with significant effects, 2 patients with some improvement and 2 patients had no response in the sulperazone group, and 4 patients did not survive after 28 days. In conclusion, the combined therapy of cefoperazone or sulbactam supplemented with tanreqing was identified to be more effective than cefoperazone or sulbactam as monotherapy, for treating multidrug resistant Acinetobacter baumannii.
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spelling pubmed-48124382016-04-12 Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection PAN, TAO LIU, XIAOYUN XIANG, SHOUGUI JI, WENLI Exp Ther Med Articles Bacterial infections are common but have become increasingly resistant to drugs. The aim of the present study was to examine the combined treatment of traditional Chinese and Western medicine in 30 cases of pulmonary infection with multidrug resistant Acinetobacter baumannii. Patients were divided into groups A and B according to drug treatments. Cefoperazone or sulbactam and tanreqing were administered in group A, and cefoperazone or sulbactam in group B. The curative effect and prognosis of the two groups were recorded and the remaining treatments were performed routinely in the clinic. For the combined therapy group, which was administered sulperazone and tanreqing, 8 patients were recovered, 6 patients had significant effects, 3 patients exhibited some improvement and 1 patient had no response. One of the patients did not survive after 28 days. By contrast, there were 4 patients that were successfully treated, 3 patients with significant effects, 2 patients with some improvement and 2 patients had no response in the sulperazone group, and 4 patients did not survive after 28 days. In conclusion, the combined therapy of cefoperazone or sulbactam supplemented with tanreqing was identified to be more effective than cefoperazone or sulbactam as monotherapy, for treating multidrug resistant Acinetobacter baumannii. D.A. Spandidos 2016-04 2016-02-08 /pmc/articles/PMC4812438/ /pubmed/27073447 http://dx.doi.org/10.3892/etm.2016.3051 Text en Copyright: © Pan et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
PAN, TAO
LIU, XIAOYUN
XIANG, SHOUGUI
JI, WENLI
Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection
title Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection
title_full Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection
title_fullStr Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection
title_full_unstemmed Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection
title_short Treatment for patients with multidrug resistant Acinetobacter baumannii pulmonary infection
title_sort treatment for patients with multidrug resistant acinetobacter baumannii pulmonary infection
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812438/
https://www.ncbi.nlm.nih.gov/pubmed/27073447
http://dx.doi.org/10.3892/etm.2016.3051
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