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Protective Effect of Tempol on Buthionine Sulfoximine-Induced Mitochondrial Impairment in Hippocampal Derived HT22 Cells

Using a simulated oxidative stress model of hippocampus-derived immortalized cell line (HT22), we report that prooxidant buthionine sulfoximine (BSO, 1 mM, 14 h), without adversely affecting cell viability or morphology, induced oxidative stress by inhibiting glutathione synthesis. BSO treatment als...

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Detalles Bibliográficos
Autores principales:	Salvi, Ankita, Patki, Gaurav, Khan, Eisha, Asghar, Mohammad, Salim, Samina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812466/ https://www.ncbi.nlm.nih.gov/pubmed/27069531 http://dx.doi.org/10.1155/2016/5059043

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