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Effects of decitabine on megakaryocyte maturation in patients with myelodysplastic syndromes

Thrombocytopenia is a common, often fatal complication experienced by patients with myelodysplastic syndromes (MDS). 5-aza-2′-deoxycytidine (decitabine) has been used to treat MDS patients with thrombocytopenia with a response rate of 45–50%. However, the mechanism of its effects on megakaryocytes r...

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Detalles Bibliográficos
Autores principales:	DING, KAI, FU, RONG, LIU, HUI, NACHNANI, DEEPAK ANIL, SHAO, ZONG-HONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812569/ https://www.ncbi.nlm.nih.gov/pubmed/27073478 http://dx.doi.org/10.3892/ol.2016.4259

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