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ASF-4-1 fibroblast-rich culture increases chemoresistance and mTOR expression of pancreatic cancer BxPC-3 cells at the invasive front in vitro, and promotes tumor growth and invasion in vivo

Pancreatic cancer develops dense stromal tissue through the desmoplastic reaction. The aim of the present study was to assess the effects of a fibroblast-rich environment on the malignant potential of pancreatic cancer. Cells from the human pancreatic cancer cell line BxPC-3 were mixed at a ratio of...

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Detalles Bibliográficos
Autores principales: FUJIWARA, MASAYA, KANAYAMA, KAZUKI, HIROKAWA, YOSHIFUMI S., SHIRAISHI, TAIZO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812595/
https://www.ncbi.nlm.nih.gov/pubmed/27073551
http://dx.doi.org/10.3892/ol.2016.4289

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