Identification of Human UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the Glucuronidation of 20(S)-Protopanaxadiol in Human Liver Microsomes

20(S)-protopanaxadiol (PPD), one of the representative aglycones of ginsenosides, has a broad spectrum of pharmacological activities. Although phase I metabolism has been investigated extensively, information regarding phase II metabolism of this compound remains to be elucidated. Here, a glucuronid...

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Detalles Bibliográficos
Autores principales: Li, Jia, He, Chunyong, Fang, Lianxiang, Yang, Li, Wang, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813125/
https://www.ncbi.nlm.nih.gov/pubmed/27005621
http://dx.doi.org/10.3390/ijms17030205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813125/
https://www.ncbi.nlm.nih.gov/pubmed/27005621
http://dx.doi.org/10.3390/ijms17030205

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