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Integrative Analyses of miRNA-mRNA Interactions Reveal let-7b, miR-128 and MAPK Pathway Involvement in Muscle Mass Loss in Sex-Linked Dwarf Chickens

The sex-linked dwarf (SLD) chicken is an ideal model system for understanding growth hormone (GH)-action and growth hormone receptor (GHR) function because of its recessive mutation in the GHR gene. Skeletal muscle mass is reduced in the SLD chicken with a smaller muscle fiber diameter. Our previous...

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Detalles Bibliográficos
Autores principales: Luo, Wen, Lin, Shumao, Li, Guihuan, Nie, Qinghua, Zhang, Xiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813140/
https://www.ncbi.nlm.nih.gov/pubmed/26927061
http://dx.doi.org/10.3390/ijms17030276