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Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism

Pyrrolizidine Alkaloids (PAs) are currently one of the most important botanical hepatotoxic ingredients. Glutathion (GSH) metabolism is the most reported pathway involved in hepatotoxicity mechanism of PAs. We speculate that, for different PAs, there should be a common mechanism underlying their hep...

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Detalles Bibliográficos
Autores principales:	Yan, Xinmiao, Kang, Hong, Feng, Jun, Yang, Yiyan, Tang, Kailin, Zhu, Ruixin, Yang, Li, Wang, Zhengtao, Cao, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813181/ https://www.ncbi.nlm.nih.gov/pubmed/26959016 http://dx.doi.org/10.3390/ijms17030318

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