Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers

Monoclonal antibodies are the dominant agents used in inhibition of biological target molecules for disease therapeutics, but there are concerns of immunogenicity, production, cost and stability. Oligonucleotide aptamers have comparable affinity and specificity to targets with monoclonal antibodies...

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Detalles Bibliográficos
Autores principales: Yu, Yuanyuan, Liang, Chao, Lv, Quanxia, Li, Defang, Xu, Xuegong, Liu, Baoqin, Lu, Aiping, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813219/
https://www.ncbi.nlm.nih.gov/pubmed/26978355
http://dx.doi.org/10.3390/ijms17030358

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