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Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium
Stem cells hold promise for treating a wide variety of diseases, including degenerative disorders of the eye. The eye is an ideal organ for stem cell therapy because of its relative immunological privilege, surgical accessibility, and its being a self-contained system. The eye also has many potentia...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813266/ https://www.ncbi.nlm.nih.gov/pubmed/27102165 http://dx.doi.org/10.3390/ijms17030415 |
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author | Ouyang, Hong Goldberg, Jeffrey L. Chen, Shuyi Li, Wei Xu, Guo-Tong Li, Wei Zhang, Kang Nussenblatt, Robert B. Liu, Yizhi Xie, Ting Chan, Chi-Chao Zack, Donald J. |
author_facet | Ouyang, Hong Goldberg, Jeffrey L. Chen, Shuyi Li, Wei Xu, Guo-Tong Li, Wei Zhang, Kang Nussenblatt, Robert B. Liu, Yizhi Xie, Ting Chan, Chi-Chao Zack, Donald J. |
author_sort | Ouyang, Hong |
collection | PubMed |
description | Stem cells hold promise for treating a wide variety of diseases, including degenerative disorders of the eye. The eye is an ideal organ for stem cell therapy because of its relative immunological privilege, surgical accessibility, and its being a self-contained system. The eye also has many potential target diseases amenable to stem cell-based treatment, such as corneal limbal stem cell deficiency, glaucoma, age-related macular degeneration (AMD), and retinitis pigmentosa (RP). Among them, AMD and glaucoma are the two most common diseases, affecting over 200 million people worldwide. Recent results on the clinical trial of retinal pigment epithelial (RPE) cells from human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) in treating dry AMD and Stargardt’s disease in the US, Japan, England, and China have generated great excitement and hope. This marks the beginning of the ocular stem cell therapy era. The recent Zhongshan Ophthalmic Center Ocular Stem Cell Symposium discussed the potential applications of various stem cell types in stem cell-based therapies, drug discoveries and tissue engineering for treating ocular diseases. |
format | Online Article Text |
id | pubmed-4813266 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-48132662016-04-06 Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium Ouyang, Hong Goldberg, Jeffrey L. Chen, Shuyi Li, Wei Xu, Guo-Tong Li, Wei Zhang, Kang Nussenblatt, Robert B. Liu, Yizhi Xie, Ting Chan, Chi-Chao Zack, Donald J. Int J Mol Sci Conference Report Stem cells hold promise for treating a wide variety of diseases, including degenerative disorders of the eye. The eye is an ideal organ for stem cell therapy because of its relative immunological privilege, surgical accessibility, and its being a self-contained system. The eye also has many potential target diseases amenable to stem cell-based treatment, such as corneal limbal stem cell deficiency, glaucoma, age-related macular degeneration (AMD), and retinitis pigmentosa (RP). Among them, AMD and glaucoma are the two most common diseases, affecting over 200 million people worldwide. Recent results on the clinical trial of retinal pigment epithelial (RPE) cells from human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) in treating dry AMD and Stargardt’s disease in the US, Japan, England, and China have generated great excitement and hope. This marks the beginning of the ocular stem cell therapy era. The recent Zhongshan Ophthalmic Center Ocular Stem Cell Symposium discussed the potential applications of various stem cell types in stem cell-based therapies, drug discoveries and tissue engineering for treating ocular diseases. MDPI 2016-03-22 /pmc/articles/PMC4813266/ /pubmed/27102165 http://dx.doi.org/10.3390/ijms17030415 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Conference Report Ouyang, Hong Goldberg, Jeffrey L. Chen, Shuyi Li, Wei Xu, Guo-Tong Li, Wei Zhang, Kang Nussenblatt, Robert B. Liu, Yizhi Xie, Ting Chan, Chi-Chao Zack, Donald J. Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium |
title | Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium |
title_full | Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium |
title_fullStr | Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium |
title_full_unstemmed | Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium |
title_short | Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium |
title_sort | ocular stem cell research from basic science to clinical application: a report from zhongshan ophthalmic center ocular stem cell symposium |
topic | Conference Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813266/ https://www.ncbi.nlm.nih.gov/pubmed/27102165 http://dx.doi.org/10.3390/ijms17030415 |
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