Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis

Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse ch...

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Detalles Bibliográficos
Autores principales: Qin, Li, Zhu, Neng, Ao, Bao-Xue, Liu, Chan, Shi, Ya-Ning, Du, Ke, Chen, Jian-Xiong, Zheng, Xi-Long, Liao, Duan-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813279/
https://www.ncbi.nlm.nih.gov/pubmed/27011179
http://dx.doi.org/10.3390/ijms17030429
Descripción
Sumario:Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse cholesterol transport and inflammation in atherosclerosis can be integrated by caveolae and caveolin-1.

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