Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis

Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse ch...

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Autores principales: Qin, Li, Zhu, Neng, Ao, Bao-Xue, Liu, Chan, Shi, Ya-Ning, Du, Ke, Chen, Jian-Xiong, Zheng, Xi-Long, Liao, Duan-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813279/
https://www.ncbi.nlm.nih.gov/pubmed/27011179
http://dx.doi.org/10.3390/ijms17030429
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author Qin, Li
Zhu, Neng
Ao, Bao-Xue
Liu, Chan
Shi, Ya-Ning
Du, Ke
Chen, Jian-Xiong
Zheng, Xi-Long
Liao, Duan-Fang
author_facet Qin, Li
Zhu, Neng
Ao, Bao-Xue
Liu, Chan
Shi, Ya-Ning
Du, Ke
Chen, Jian-Xiong
Zheng, Xi-Long
Liao, Duan-Fang
author_sort Qin, Li
collection PubMed
description Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse cholesterol transport and inflammation in atherosclerosis can be integrated by caveolae and caveolin-1.
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spelling pubmed-48132792016-04-06 Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis Qin, Li Zhu, Neng Ao, Bao-Xue Liu, Chan Shi, Ya-Ning Du, Ke Chen, Jian-Xiong Zheng, Xi-Long Liao, Duan-Fang Int J Mol Sci Review Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse cholesterol transport and inflammation in atherosclerosis can be integrated by caveolae and caveolin-1. MDPI 2016-03-22 /pmc/articles/PMC4813279/ /pubmed/27011179 http://dx.doi.org/10.3390/ijms17030429 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Qin, Li
Zhu, Neng
Ao, Bao-Xue
Liu, Chan
Shi, Ya-Ning
Du, Ke
Chen, Jian-Xiong
Zheng, Xi-Long
Liao, Duan-Fang
Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis
title Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis
title_full Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis
title_fullStr Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis
title_full_unstemmed Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis
title_short Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis
title_sort caveolae and caveolin-1 integrate reverse cholesterol transport and inflammation in atherosclerosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813279/
https://www.ncbi.nlm.nih.gov/pubmed/27011179
http://dx.doi.org/10.3390/ijms17030429
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