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Nanog induces suppression of senescence through downregulation of p27(KIP1) expression

A comprehensive analysis of the molecular network of cellular factors establishing and maintaining pluripotency as well as self renewal of pluripotent stem cells is key for further progress in understanding basic stem cell biology. Nanog is necessary for the natural induction of pluripotency in earl...

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Detalles Bibliográficos
Autores principales: Münst, Bernhard, Thier, Marc Christian, Winnemöller, Dirk, Helfen, Martina, Thummer, Rajkumar P., Edenhofer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813312/
https://www.ncbi.nlm.nih.gov/pubmed/26795560
http://dx.doi.org/10.1242/jcs.167932