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Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor
A bacterial collagen-like protein Scl2 has been developed as a recombinant collagen model system to host human collagen ligand-binding sequences, with the goal of generating biomaterials with selective collagen bioactivities. Defined binding sites in human collagen for integrins, fibronectin, hepari...
Autores principales: | An, Bo, Abbonante, Vittorio, Xu, Huifang, Gavriilidou, Despoina, Yoshizumi, Ayumi, Bihan, Dominique, Farndale, Richard W., Kaplan, David L., Balduini, Alessandra, Leitinger, Birgit, Brodsky, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813464/ https://www.ncbi.nlm.nih.gov/pubmed/26702058 http://dx.doi.org/10.1074/jbc.M115.674507 |
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