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Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris

The alcohol oxidase 1 (AOX1) promoter (P(AOX1)) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)(2)Cys(6)-type methanol-induced transcription factor...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaolong, Wang, Qi, Wang, Jinjia, Bai, Peng, Shi, Lei, Shen, Wei, Zhou, Mian, Zhou, Xiangshan, Zhang, Yuanxing, Cai, Menghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813576/ https://www.ncbi.nlm.nih.gov/pubmed/26828066 http://dx.doi.org/10.1074/jbc.M115.692053

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