Control of Foxp3 stability through modulation of TET activity

Ten-eleven translocation (TET) enzymes oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine and other oxidized methylcytosines, intermediates in DNA demethylation. In this study, we examine the role of TET proteins in regulating Foxp3, a transcription factor essential for the development and fu...

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Detalles Bibliográficos
Autores principales: Yue, Xiaojing, Trifari, Sara, Äijö, Tarmo, Tsagaratou, Ageliki, Pastor, William A., Zepeda-Martínez, Jorge A., Lio, Chan-Wang J., Li, Xiang, Huang, Yun, Vijayanand, Pandurangan, Lähdesmäki, Harri, Rao, Anjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813667/
https://www.ncbi.nlm.nih.gov/pubmed/26903244
http://dx.doi.org/10.1084/jem.20151438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813667/
https://www.ncbi.nlm.nih.gov/pubmed/26903244
http://dx.doi.org/10.1084/jem.20151438

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